Cell and molecular bases

Hernández-Bule ML, Trillo, Martínez-García MA, Abilahoud C, Úbeda A. Chondrogenic Differentiation of Adipose-Derived Stem Cells by Radiofrequency Electric Stimulation. Journal of Stem Cell Research & Therapy. 2017;7(12): 10.

Spottorno J, González de Vega C, Buenaventura M, Hernando A. (2017). “Influence of electrodes on the 448 kHz electric currents created by radiofrequency: A finite element study.” Electromagn Biol Med 36(3): 306-314.

Hernández-Bule ML, Martinez-Botas J, Trillo MA, Paino CL, Ubeda A. Antiadipogenic Effects of Subthermal Electric Stimulation at 448 kHz on Differentiating Human Mesenchymal Stem Cells. Mol Med Rep,2016; 13, (5): 3895-903.

Hernández-Bule ML, Paino CL, Trillo MA, Ubeda A. Electric Stimulation at 448 kHz Promotes Proliferation of Human Mesenchymal Stem Cells. Cell Physiol Biochem. 2014;34(5): 1741-55.


Yokota Y, Sonoda T, Tashiro Y, Suzuki Y, Kajiwara Y, Zeidan H, et al. Effect of Capacitive and Resistive electric transfer on changes in muscle flexibility and lumbopelvic alignment after fatiguing exercise. Journal of physical therapy science. 2018;30(5):719-25.

Yokota Y, Tashiro Y, Suzuki Y, Tasaka S, Matsushita T, Matsubara K, Kawagoe M, Sonoda T, Nakayama Y, Hasegawa S, Aoyama T. Effect of Capacitive and Resistive Electric Transfer on Tissue Temperature, Muscle Flexibility, and Blood Circulation. J Nov Physiother. 2017;07(01).

Kumaran B, Herbland A, Watson T. Continuous-Mode 448 kHz Capacitive Resistive Monopolar Radiofrequency Induces Greater Deep Blood Flow Changes Compared to Pulsed Mode Shortwave: A Crossover Study in Healthy Adults. European Journal of Physiotherapy. 2017;19(3): 137-46.

Kumaran B, Watson T. Thermal build-up, decay and retention responses to local therapeutic application of 448 kHz capacitive resistive monopolar radiofrequency: A prospective randomised crossover study in healthy adults. Int J Hyperthermia. 2015; 31(8): 883-895.


Inflammation / Oedema

Naranjo P, López Andrino R, Pinto H. First Assessment of the Proionic Effects Resulting from Non-Thermal Application of 448 kHz Monopolar Radiofrequency for Reduction of Edema Caused by Fractional CO2 Laser Facial Rejuvenation Treatments. Journal of Surgery. 2015:3(1): 21.

Naranjo P, López R, Pinto H. Reduction of erythema after laser on rosacea by subthermal 448 kHz monopolar radiofrequency. IJDR. 2015;5(3): 3775-3777.

Regeneration / Scarring

Armenesi R. Effetti della biostimolazione con la tecnologia INDIBA Deep Care sulle ustioni in fase acuta [Minor]. Bari: Università degli studi di Bari “Aldo Moro”; 2017.

Manzari A. L’impiego del dispositivo INDIBA Deep Care nel Trattamento delle ustioni in fase acuta [Minor]: Università degli studi di Bari Aldo Moro; 2017

Favia D. Impiego della terapia cellulare attiva nel trattamento delle ipertrofie cicatriziali precoci da ustione [Minor]: Università degli Studi di Bari Aldo Moro; 2017

Colella M. Uso Integrato Di Terapia Cellulare Attiva E Onde D’urto Nella Fase Di Stabilizzazione Cicatriziale Post-Ustione. Università degli studi di bari Aldo Moro., 2015.

Sette A. Trattamento Delle Cicatrici Ipertrofiche Post-Ustione Con Terapia Cellulare Attiva. Università degli studi di bari Aldo Moro., 2015.

Aesthetic medicine

Carvalho GF, de Mesquita Filho J, Froes Meyer P, Ariel Ronzio O, Medeiros de Oliveira J, Martins Nóbrega M, Arend Barichello P, de Mendonça W, de Souza Fernandes A, Lima Cavalcante J, da Silva R. Avaliaçao Dos Efeitos Da Radiofrequência No Tecido Conjuntivo. Rev. Bras. Med. 2011;68:10-24

Yupakorn K, Amornvittayachan O, Udompataikul M. Efficacy of Monopolar Radiofrequency Device on Cellulite Treatment. Srinagarind Med J. 2010;25(4): 258-64.

Pinto R. Radiofrecuencia Monopolar Capacitiva / Resistiva De 0.5 mHz En El Envejecimiento Cutáneo Facial. Medicina estética. 2009;20: 32-37.

Pinto R. Radiofrecuencia Monopolar Capacitiva/Resistiva De 0,5 mHz En Celulitis. Medicina estética. 2009;19.

Shin SU, Choi YM, Shim WJ, Lee HC, Kim KS. Effects of High Frequency Therapy on Localized Obesity. Journal of Korean Oriental Association for Study of Obesity. 2006;6(2):75-83. [Korean]


Combination with PRP

Fernández-Galiano B, Gómez-Domínguez S. Structural changes in recalcitrant epitrochlear tendinopathy after the combined application of percutaneous needle electrolysis, PRP and active biological stimulus in a professional tennis player. J Invasive Tech Phys Ther. 2016;1(2):2.


Bito T, Tashiro Y, Suzuki Y, Kajiwara Y, Zeidan H, Kawagoe M, et al. Acute Effects of Capacitive and Resistive electric transfer on the Achilles tendon. Electromagnetic Biology and Medicine. 2018.


Alguacil Diego IMA, Fernandez-Carnero J, Val SL, Cano-de-la-Cuerda R, Calvo-Lobo C, Piedrola RM, et al. Analgesic effects of a capacitive-resistive monopolar radiofrequency in patients with myofascial chronic neck pain: a pilot randomized controlled trial. Revista da Associacao Medica Brasileira (1992). 2019;65(2):156-64.

Takahashi K, Suyama T, Onodera M, Hirabayashi S, Tsuzuki N, Zhong-Shi L. Clinical Effects of Capacitive Electric Transfer Hyperthermia Therapy for Cervico-Omo-Brachial Pain. J. Phys. Ther. Sci. 2000;12: 43-48.

Takahashi K, Suyama T, Onodera M, Hirabayashi S, Tsuzuki N, Zhong-Shi L. Clinical Effects of Capacitive Electric Transfer Hyperthermia Therapy for Lumbago. J. Phys. Ther. Sci. 1999;11: 45-51.


Kumaran B, Watson T. Treatment using 448kHz capacitive resistive monopolar radiofrequency improves pain and function in patients with osteoarthritis of the knee joint: a randomized controlled trial. Physiotherapy. 2019;105(1):98-107.


Terranova A, Vermiglio G. Arena S. Cicciòe A, di Dio S, Vermiglio M. Monopolar Capacitive Resistive Radiofrequency 448 kHz in the femur fracture post-chirurgical treatment. Eur Med Phys. 2008;44(Suppl 1)(3):1-2

Pelvic Health

Pavone C, Castrianni D, Romeo S, Napoli E, Usala M, Gambino G, et al. TECAR therapy for Peyronie’s disease: a phase-one prospective study. Great evidence in patients with erectile dysfunction. Urologia. 2013;80(2):148-53.

Cortés C. Radiofrecuencia Monopolar Capacitiva/Resistiva (Rfm Cap/Res), Sistema Indiba, en el tratamiento fisioterápico de disfunciones del suelo pélvico. Barcelona: Universitat Pompeu Fabra, 2012.

Oh MM, Jin MH, Moon DG, Nam SG, Bae JH, Park SH. A Prospective, Randomized, Placebo Controlled Study of Radiofrequency Therapy for the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome. J Urol. 2009; Vol. 181(4), Supplement, Sunday): 122. 

Serra ML, Martinez S. Tratamiento Fisioterápico de La Hipertonía del Suelo Pélvico. UROD A. 2007;20(2): 74-83.

Corona Virus (COVID-19) Update
As we continue to monitor the situation with Coronavirus (COVID-19), we are taking steps to help protect the health and well-being of our customers and partners. Please proceed to our information hub to learn about the latest updates.